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Antimullerian hormone levels in women with polycystic ovarian syndrome and infertility before and after metformin therapy.

Antimullerian hormone levels in women with polycystic ovarian syndrome and infertility before and after metformin therapy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/059087
Enrollment
50
Registered
2023-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E70-E88- Metabolic disorders

Interventions

Intervention1: Tablet Metformin: After TVS scan (for ovarian volume and antral follicular count) and serum AMH assessment, patient will be administered:- Tab Metformin 500 mg once a day orally for fir

Sponsors

Teerthankar Mahaveer medical college and research centre,Moradabad UP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)PCOS Patients Based on the 2003 Rotterdam consensus, the three diagnostic criteria of PCOS are:- -Oligo-and/or anovulation (OA), -Hyperandrogenism -Ultrasound feature of polycystic ovaries:-(Presence of more than 12 follicles with a diameter of 2–9 mm or when the ovarian volume is more than 10mm at least in 1 ovary). 2)Age (18-45 years) 3)Infertility 4) No contraindications for oral administration of metformin 5) No administration of metformin within the previous four months 6) No administration of oral contraception within two months prior to the study. 7) No medication affecting gonadal or adrenal function, carbohydrate or lipid metabolism.

Exclusion criteria

Exclusion criteria: 1)Metformin intolerance. 2) Thyroid dysfunction 3)Diabetes mellitus 4) Hyperprolactinemia

Design outcomes

Primary

MeasureTime frame
Changes in serum AMH levels. Timepoint: 8 weeks

Secondary

MeasureTime frame
Changes in antral follicle counts. Timepoint: 8 weeks

Countries

India

Contacts

Public ContactDr Shivangi Singhal

Teerthankar Mahaveer medical college and research centre,Moradabad UP

drkanchanrani@gmail.com9756216630

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026