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Comparison of bone grafts in treatment of bony defects

Comparative evaluation of bioactive calcium phosphosilicate graft with enamel matrix derivative in the treatment of three wall intrabony defects: A Randomized Controlled Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/059043
Enrollment
45
Registered
2023-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K053- Chronic periodontitis

Interventions

Intervention1: Open Flap Debridement: Clinical parameters like gingival index, plaque index, probing depth, clinical attachment level and radiographic assessment will be done at baseline and at 6 mont

Sponsors

Dr Anjali Batra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria 1. Patients in the age group of 18-45 years. 2. Patients with probing pocket depth > 6 mm and clinical attachment level > 8 mm. 3. Patients with three wall intrabony defects in mandibular posterior teeth. 4. Patients willing to keep appointments. Exclusion criteria 1. Patients on medication for systemic diseases. 2. Patients undergone regenerative periodontal therapy last 6 months. 3. Patients on antibiotics and non-steroidal anti-inflammatory analgesic therapy in last 3 months. 4. Test and control sites involving caries and any kind of prosthesis. 5. Pregnant and lactating females. 6. Patients with history of allergy to synthetic grafts and EMD. 7. Patients on hormone replacement therapy. 8. Patients refusing to give consent for EMD. 9. Patients using any form of tobacco.

Exclusion criteria

Exclusion criteria: Inclusion criteria 1. Patients in the age group of 18-45 years. 2. Patients with probing pocket depth > 6 mm and clinical attachment level > 8 mm. 3. Patients with three wall intrabony defects in mandibular posterior teeth. 4. Patients willing to keep appointments. Exclusion criteria 1. Patients on medication for systemic diseases. 2. Patients undergone regenerative periodontal therapy last 6 months. 3. Patients on antibiotics and non-steroidal anti-inflammatory analgesic therapy in last 3 months. 4. Test and control sites involving caries and any kind of prosthesis. 5. Pregnant and lactating females. 6. Patients with history of allergy to synthetic grafts and EMD. 7. Patients on hormone replacement therapy. 8. Patients refusing to give consent for EMD. 9. Patients using any form of tobacco.

Design outcomes

Primary

MeasureTime frame
Primary- There is no difference seen in clinical parameters and bone fill levels in patients with or without graft placement. Timepoint: Baseline, 3 month, 6 month—

Secondary

MeasureTime frame
Clinical parameters like gingival index, plaque index, probing depth, clinical attachment level & radiographic assessment will be done at baseline & at 6 months Timepoint: Baseline, 3 month, 6 month—

Countries

India

Contacts

Public ContactANJALI BATRA

MANAV RACHNA DENTAL COLLEGE

ruchi.sds@mrei.ac.in7799690877

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026