Comparision of topical kojic acid and topical tranexamic acid in patients of post inflammatory hyperpigmentation

STUDY BETWEEN TOPICAL TRANEXAMIC ACID WITH ORAL TRANEXAMIC ACID AND TOPICAL KOJIC ACID WITH ORAL TRANEXAMIC ACID IN TREATMENT OF POST INFLAMMATORY HYPERPIMENTATION - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/059029

Enrollment

Registered

2023-10-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L810- Postinflammatory hyperpigmentation

Interventions

Intervention1: Topical Tranexamic acid with Oral Tranexamic acid vs Topical Kojic acid and oral Tranexamic acid: Patients in group A will be given topical tranexamic acid -3% and oral tranexamic acid

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with post inflammatory hyperpigmentation, presenting to dermatology outpatient department. 2. Patients of both genders and age group 18-50 years old. 3. Patients willing with informed consent to participate in the study. 4. Patients with normal coagulation profile (bleeding time and clotting time).

Exclusion criteria

Exclusion criteria: 1. Patients having uncontrolled medical or surgical illness and other major systemic diseases. 2. Patients who are not willing for the study or follow-up. 3. Patients who had preexisting bleeding, coagulation, thromboembolic, or psychological disorders. 4. Patients not willing for the study or for follow-up. 5. Patients with pregnancy or on lactation or oral contraceptives

Design outcomes

Primary

Measure	Time frame
decrease in pigmentationTimepoint: zero, four, eight and twelve weeks	—

Secondary

Measure	Time frame
any irritation with the productsTimepoint: zero, four, eight and twelve weeks	—

Countries

India

Contacts

Public ContactDr Ishita Choudhary

Mahatma Gandhi Medical College and Hospital

mnijhawan12@gmail.com09166295451

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026