Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: 0.5% Bupivacaine 17.5mg (3.5ml) with 50µg Clonidine: 0.5% bupivacaine 17.5mg (3.5ml) with 50µg Clonidine (in 0.5ml normal saline) (Total volume-4ml) . The sensory block level wil
Sponsors
DR SOMSUNDAR R G
DR SHARMILA SHERIN
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients who are posted for elective gynecological surgeries. 2.Age group 18-60 years. 3.American Society of Anesthesiologists (ASA) grades I and II. 4.Patients with Body Mass Index (BMI) between 18.5-24.9. 5.Patients with height ranging between 150 cm and 180 cm . 6.Patients who are willing to participate in the study with informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients taking alpha-adrenergic receptor antagonists, calcium channel blockers and angiotensin converting enzyme inhibitors 2.Patients having any absolute contraindications for spinal anaesthesia like increased intracranial tension, severe hypovolemia, history of bleeding diathesis and local infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect and adverse effect of intrathecal Clonidine versus Dexmedetomidine versus 0.9% Saline as adjuvants to 0.5% Hyperbaric Bupivacaine in subarachnoid block in patients undergoing elective gynaecological surgeries by using the following parameters: 1. Duration of analgesia. 2. To assess the onset and duration of motor block. Timepoint: BASAL , 2 MIN , 5 MIN , 10 MIN , 20 MIN , 30 MIN , 40 MIN , 50 MIN , 60 MIN , 70 MIN , 80 MIN , 90 MIN , 120 MIN , 140 MIN , 160 MIN , 180 MIN | — |
Secondary
| Measure | Time frame |
|---|---|
| Peri-operative hemodynamic changes and adverse effectsTimepoint: 2 HOURS , 8 HOURS , 12 HOURS , 24 HOURS | — |
Countries
India
Contacts
Public ContactDR Sharmila Sherin
Mandya Institute Of Medical Sciences
Outcome results
None listed