Health Condition 1: - Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Evaluating miRNA 210 in pre eclampsia women as prognostic marker: Evaluating miRNA 210 in pre eclampsia women by genetic analyis- Serum isolation is obtained by centrifugation at 1600 r
Sponsors
DR KOTA SAI MEGHANA
Eligibility
Inclusion criteria
Inclusion criteria: 1 Any pregnant woman with BP more than or equal to 140/90mmhg with two readings measured 6 hours apart with significant proteinuria (more than or equal to 300 mg of protein in a 24hr urine specimen or more than or equal to 1+ by dipstick) following 20 weeks of gestation in a previously normotensive woman 2 Pregnant women age more than or equal to 18 3 Singleton pregnancy 4 Prenatal care at BLDE
Exclusion criteria
Exclusion criteria: 1 Any congenital fetal malformations or chromosomal abnormalities 2 Chronic Hypertension 3 Twins with pre eclampsia 4 Renal disease with pre eclampsia 5 Cardiac disease with pre eclampsia 6 Recent infection 7 APLA Syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the upregulation of miRNA 210 gene in pre-eclamptic women compared to normal healthy pregnant womenTimepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the severity of pre-eclampsia in pregnant women with the gene expression. To correlate the fetal outcome with respect to fetal growth restriction, oligohydramnios, low birth weight, neonatal asphyxia, NICU admission. Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactK SAI MEGHANA
SHRI B M PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE
Outcome results
None listed