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Analgesic efficacy of 2 different drugs are compared based on the Pain scale in post op

Effect of 0.1%ropivacaine with dexmedetomidine compared to 0.125%bupivacaine with dexmedetomidine in ultrasound guided femoral nerve block for post-operative analgesia after total-knee arthroplasty – A comparative observational study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/059011
Enrollment
72
Registered
2023-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: nil: nil

Sponsors

Dr Manjesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.The patients undergoing unilateral total knee arthroplasty under spinal anesthesia. 2.ASA grade I, II & III

Exclusion criteria

Exclusion criteria: 1.Patients who are not willing to participate in the study. 2.Patient with a history of allergy to the drugs used in the study. 3.Patients with infection at the site of femoral nerve block. 4.Patients with pre-existing peripheral neuropathy. 5.Patients with impaired renal and liver function, coagulopathy. 6.Patients with documented history of opioid sensitivity and/or allergy to NSAIDs.

Design outcomes

Primary

MeasureTime frame
analgesic efficacy of 0.125%bupivacaine is better than 0.125%ropivacaine.Timepoint: At 30 min,1hr,2hr,4hr,6hr,12hr and 24hr post op.—

Secondary

MeasureTime frame
To assess the side effects over 24 hours post-operative period between the groups.Timepoint: Post op period—

Countries

India

Contacts

Public ContactDr Sumesh T Rao

Kasturba Medical College, Mangalore

drstrao@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026