A comparative study between chest wall nerve block vs conventional IV analgesics for post-operative pain management in breast cancer patients undergoing modified radical mastectomy.

A randomized comparative study between surgically-guided serratus anterior plane block vs conventional IV analgesics for post-operative pain management in breast cancer patients undergoing modified radical mastectomy. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058992

Enrollment

Registered

2023-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Surgically guided serratus anterior plane block. During surgery, a 18 G catheter is tunneled subcutaneously by Tuohy needle and placed between serratus anterior muscle and ribs. For SAP

Eligibility

Inclusion criteria

Inclusion criteria: Adult female patients aged =18 year who will undergo elective MRM surgery at the RIMS, RANCHI and who met the criteria of classes I–III of the American Society of Anesthesiology (ASA) classification will be eligible for inclusion in the study

Exclusion criteria

Exclusion criteria: Age criteria. Also, patients who would unconscious or mentally incompetent prior to surgery, or who would in ASA classes IV or V, or had coagulopathy or hemodynamic instability (systolic blood pressure allergic reactions to opiates or to local anesthetic agents wil be excluded from the study

Design outcomes

Primary

Measure	Time frame
Assessment of the level of post-operative pain (on NRS scores) Timepoint: Post-operative pain on NRS score at post-op 0,1,2,4,12 and 24 hours.	—

Secondary

Measure	Time frame
(1) Time needed to the first rescue analgesic in minutes. (2) Cumulative dose of rescue analgesic needed (cumulative dose of tramadol & fentanyl). (3)Rate of patient satisfaction (on a 1 to 10 scale). (4)The incidence of nausea & any attack of post-operative vomiting (5)The incidence of any of the serratus anterior plane blocks complications e.g. injection site hematoma or signs or symptoms of local anesthetic toxicity. Timepoint: post-op period upto patient discharge.	—

Measure

Time frame

(1) Time needed to the first rescue analgesic in minutes. (2) Cumulative dose of rescue analgesic needed (cumulative dose of tramadol & fentanyl). (3)Rate of patient satisfaction (on a 1 to 10 scale). (4)The incidence of nausea & any attack of post-operative vomiting (5)The incidence of any of the serratus anterior plane blocks complications e.g. injection site hematoma or signs or symptoms of local anesthetic toxicity. Timepoint: post-op period upto patient discharge.

—

Countries

India

Contacts

Public ContactDr Ladhu Lakra

RIMS, RANCHI

dr.ladhulakra007@gmail.com9835160608

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026