Health Condition 1: P399- Infection specific to the perinatal period, unspecified
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
Bharati Vidyapeeth Deemed University Medical College, Pune
Eligibility
Inclusion criteria
Inclusion criteria: Term and preterm neonates admitted to NICU during the study period and clinically suspected to have late onset sepsis ( onset after 72 hours of life)
Exclusion criteria
Exclusion criteria: 1. Moderate to severe hypoxic ischemic encephalopathy with pH 2. Congenital heart disease 3. Major congenital malformations 4. Neonates on inotropic support or received inotropes in last 24 hours at the time of enrolment 5. Haemodynamically significant patent ductus arteriosus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure myocardial performance index using targeted echocardiography in neonates with clinically suspected late onset sepsis and determine its association with proven and probable sepsisTimepoint: as soon as possible after the onset of clinical signs of sepsis and before initiation of fluid resuscitation/ inotropic support if required | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To determine the correlation between myocardial performance index and C-Reactive Protein (CRP) in neonates with late onset sepsis 2)To determine association of myocardial performance index and outcomes such as inotropic support, duration of hospital stay, mortality in neonates with late onset sepsis 3)To measure other right and left ventricular functions in neonates with suspected late onset neonatal sepsis and determine their association with late onset sepsis Timepoint: as soon as possible after the onset of clinical signs of sepsis and before initiation | — |
Countries
India
Contacts
Public ContactArshdeep Kaur
Bharati Vidyapeeth Deemed University Medical College,Pune
Outcome results
None listed