comparison of Efficacy of pain relief of Tapentadol nasal spray vs injection diclofenac following laparoscopic surgery.

Comparison of efficacy of Tapentadol nasal spray with parenteral diclofenac sodium in immediate post operative pain control following laparoscopic surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058950

Enrollment

Registered

2023-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K35-K38- Diseases of appendix Health Condition 2: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 3: K40-K46- Hernia Health Condition 4: I861- Scrotal varices Health Condition 5: O- Medical and Surgical

Interventions

Intervention1: Diclofenac sodium: Parenteral Diclofenac sodium is being used for pain control. duration of intervention is till 7 days post operative period. Control Intervention1: Tapentadol: Tapenta

Eligibility

Inclusion criteria

Inclusion criteria: patients undergoing elective laparoscopic surgeries like laparoscopic appendicectomy, laparoscopic cholecystectomy and laparoscopic hernias and varicocele under General anasthesia american society of anaesthesiologists grade I and II patients aged >18 years

Exclusion criteria

Exclusion criteria: Patients undergoing emergency surgeries. conversion to open surgery. multiple surgeries in same admission. known allergy to study drug. refusal to participate in study.

Design outcomes

Primary

Measure	Time frame
To compare the pain scores and rescue analgesia requirement in patients receiving Tapentadol nasal spray and intramuscular Diclofenac sodium injection following laparoscopic procedures.Timepoint: Twenty four hours	—

Secondary

Measure	Time frame
side effects of drug, time of mobilization and start of oral feeds, compare of satisfaction score of surgeon in post operative pain controlTimepoint: twenty four hours	—

Countries

India

Contacts

Public ContactPiyush

Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences Rohtak

surgeonpiyushgupta@gmail.com7988589889

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026