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Early vs delayed umbilical cord clamping in twin newborns born preterm

Immediate versus Delayed Umbilical Cord Clamping in preterm in Multiple Gestation: a randomized controlled trial from Western India

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058944
Enrollment
152
Registered
2023-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: delayed umbilical cord clamping: In the DCC group, after each infant is delivered and placed on the mother’s perineum in a vaginal delivery (VD) or on the thigh in a cesarean section (C

Sponsors

Dr Anitha Haribalakrishna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All preterm multiple gestation deliveries at our institute.

Exclusion criteria

Exclusion criteria: Non vigorous infant- if an infant has depressed respiration or depressed muscle tone or heart rate Prenatally diagnosed major congenital anomaly in any infants, Twin-to-twin transfusion syndrome or twin anemic-polycythemic sequence, Discordant twins (a weight di?erence of >20%), Intrauterine fetal death, Hydrops In utero transfusion/laser/amnioreduction Known cases of triplets reduced to twins Antepartum or intrapartum hemorrhage Active maternal bleeding from abruption/placental disruption at time of delivery, cord tear/avulsion

Design outcomes

Primary

MeasureTime frame
cord clamping protocol adherence rate in preterm multiple gestationTimepoint: with in first 1 minute of life

Secondary

MeasureTime frame
mortalityTimepoint: before discharge;severe Intra ventricular haemorrhageTimepoint: before discharge;periventricular leukomalaciaTimepoint: at discharge;respiratory distress syndromeTimepoint: at birth till first hour of life;necrotizing enterocolitisTimepoint: from beginning of 2nd week of life till discharge;stage 3 and or retinopathy of prematurity requiring treatmentTimepoint: at discharge;duration of mechanical ventilation in daysTimepoint: till discharge;bronchopulmonary dysplasiaTimepoint: before discharge;hemodynamically significant patent ductus arteriosus requiring treatmentTimepoint: discharge;early onset sepsisTimepoint: first 3 days of life;late onset sepsisTimepoint: after 72 hours of life till discharge;number of blood transfusions requiredTimepoint: till discharge;need of inotropesTimepoint: till discharge;highest total bilirubinTimepoint: till discharge;duration of phototherapyTimepoint: till discharge;duration of hospital stayTimepoint: till discharge;hematocrit at 6 hours of lifeTimepoint: 6 hours of life;hematocrit at 6 weeks of lifeTimepoint: 6 weeks

Countries

India

Contacts

Public ContactAnitha Haribalakrishna

Seth GS Medical College and KEM Hospital

ani.gem81@gmail.com02224107035

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 23, 2026