Health Condition 1: D561- Beta thalassemia
Conditions
Interventions
Intervention1: Curcumin capsules with curcuminoids standardised to 95%: Inlife Pharmas 500mg curcumin capsules will be given for once daily consumption to LESS THAN 10year olds and twice daily consump
Sponsors
Dr Vijay Kalrao
Eligibility
Inclusion criteria
Inclusion criteria: Subjects whose age is 5 to 18 years Patients who have been diagnosed with homozygous beta thalassemia on the basis of severe anaemia and HPLC Patients who receive packed cell RBC transfusions approximately every month. Duration of transfusion should be 6 months or more
Exclusion criteria
Exclusion criteria: Acute illness, comorbidities such as Type 1 Diabetes and/or Sickle cell. Patients taking any health supplements apart from folic acid within the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in Serum Malondialdehyde levels in test group vs control group Increase in Total Antioxidant Capacity levels in Test group vs Control groupTimepoint: Pre Intervention vs Post intervention (intervention applied for 3 months) | — |
Secondary
| Measure | Time frame |
|---|---|
| decreased mean levels of ferritin and increased mean levels of serum iron, transferrin, total iron binding capacity before and after curcumin supplementation Timepoint: Pre Intervention vs Post intervention (intervention applied for 3 months) | — |
Countries
India
Contacts
Public ContactDr Neela Vaidya
Bharati Vidyapeeth (Deemed To be) University Medical College Hospital, Pune
Outcome results
None listed