Decrease of incidence of sore throat between dexamethasone and dexmedetomidine after tracheal tube insertion.

Nebulised Dexamethasone versus Dexmedetomidine to prevent post-operative sore throat following endotracheal intubation-A Randomized Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058934

Enrollment

Registered

2023-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H661- Chronic tubotympanic suppurative otitis media

Interventions

Intervention1: Nebulisation with dexamethasone: Dexamethasone 8mg (2ml) diluted upto 5ml with Normal Saline Control Intervention1: Nebulisation with dexmedetomidine: Dexmedetomidine 1mcg/kg diluted to

Eligibility

Inclusion criteria

Inclusion criteria: Age group of 18 -60, with ASA Physical status 1-2,

Exclusion criteria

Exclusion criteria: History of preoperative sore throat, upper respiratory tract infection, known allergy to study drugs, COPD,asthma, Mallampati grade >2, more than one intubation attempt, any intraoperative or postoperative complication.

Design outcomes

Primary

Measure	Time frame
In the post anesthesia care unit, sore throat will be evaluatedTimepoint: 0,2,4,6,12 & 24 h after extubation	—

Secondary

Measure	Time frame
Hemodynamic variables - HR,MAPTimepoint: Pre-nebulisation, Pre-induction, after intubation, 0,2,4,6,12,24 after extubation	—

Countries

India

Contacts

Public ContactDr Mousumi Das

Kalinga Institute of Medical Sciences

mousumi.das1503@gmail.com9937928790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026