Comparison of heart muscle changes after giving fentanyl in patients with normal BP versus patients with high BP readings before and after undergoing laparoscopic gall bladder removal

Comparison of peri operative global longitudinal strain after administration of fentanyl in normotensive versus hypertensive patients undergoing laparoscopic cholecystectomy - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058871

Enrollment

Registered

2023-10-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: fentanyl administration: fentanyl administration at dose of 2 microgram per kg 2 minutes before laryngoscopy in hypertensive patients. Control Intervention1: fentanyl administration: fe

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I/II Controlled hypertensive patients with BP Undergoing elective laparoscopic Cholecystectomy. Normal airway with duration between laryngoscopy and endotracheal intubation

Exclusion criteria

Exclusion criteria: Refusal by patients. Any comorbitities like Diabetes mellitus,TB,COPD,Cardiac disorder,ejection fraction History of previous cardiac surgery. Diffucult airway,required more than 1 attempt. Insertion of laryngeal mask airway . BMI >30kg/metre2

Design outcomes

Primary

Measure	Time frame
To assess for Global longitudinal strain on 2D Echocardiography.Timepoint: 24 hour before and within 24 hour after laparoscopic cholecystectomy.	—

Secondary

Measure	Time frame
To assess haemodynamic changes & adverse events if anyTimepoint: Intraoperatively & within 2 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Deepak Thapa

Government Medical college and hospital , sector 32 B , Chandigarh.

dpkthapa@gmail.com9646121524

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026