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Comparison of Onset, duration, quality of postoperative analgesia of epidurally administered Bupivacaine with Dexmedetomidine group and Bupivacaine with Buprenorphine group.

comparative study of dexmedetomidine and buprenorphine as adjuvants to postoperative epidural bupivacine for analgesia in lower limb joint replacement surgeries. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058865
Enrollment
126
Registered
2023-10-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: bupivacaine with dexmedetomidine: comparison of onset of analgesia, time taken for relief of pain, duration and quality of post operative analgesia Control Intervention1: bupivacaine wi

Sponsors

vydehi institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA 1 & 2 2)PATIENTS UNDERGOING TOTAL KNEE AND HIP REPLACEMENT SURGERIES 3)Uneventful intraoperative patients

Exclusion criteria

Exclusion criteria: 1)ASA 3 & 4 2)ALLERGY TO LOCAL ANESTHETICS, DEXMEDETOMIDINE AND BUPRENORPHINE 3) BLEEDING AND NEUROMUSCULAR DISORDERS

Design outcomes

Primary

MeasureTime frame
To compare onset, duration, quality of postoperative analgesia of epidurally administered bupivacaine with dexmedetomidine and bupivacaine with buorenorphineTimepoint: To compare onset, duration, quality of postoperative analgesia of epidurally administered bupivacaine with dexmedetomidine and bupivacaine with buorenorphine—

Secondary

MeasureTime frame
assess and compare the haemodynamic parameters, side effects and time for ambulationTimepoint: after giving epidural topup onset of analgesia, sedation, duration of analgesia, haemodynamic parameters, mobilization time—

Countries

India

Contacts

Public ContactSathyanarayan j

vydehi institute of medical sciences

sathyaforall2005@gmail.com7204222070

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026