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Comparision Of Intravenous Lignocaine VS Ondansetron For Prevention OF Post Operative Nausea Vomiting In Laparoscopic Surgeries.

A Randomized Double Blinded, Comparative Study Of Intavenous Lignocaine Versus Ondansetron For Prevention Of Post Operative Nausea Vomiting In Laparoscopic Surgeries. - Nil.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058834
Enrollment
190
Registered
2023-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: INTRAVENOUS LIGNOCAINE: lignocaine 1.5mg/kg diluted to 5ml as bolus which is followed by 1.5mg/kg/hour infusion till the end of surgery. Control Intervention1: INTRAVENOUS ONDANSETRON:

Sponsors

Rajarajeswari Medical College And Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1.Adults >18years up to 70 years 2.ASA physical status I & II. 3. Ability to provide informed consent. 4.Elective laparoscopic surgery under general anaesthesia including laparoscopic cholecystectomy and laparoscopic hysterectomy.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: 1.Local anaesthesia allergy 2.Liver diseases 3.Pregnancy 4.Current tobacco use 5.Pre-existing disorders of gastrointestinal tract 6.Use of antiemetics within 48hr prior to surgery 7.Chronic use of anticholinergic medication or chronic treatment with opioids 9.Previous history of PONV 10.History of motion sickness 11.Patients having torsade de pointes, slow heart rate and prolonged QT interval on ECG.

Design outcomes

Primary

MeasureTime frame
Incidence Of Post Operative Nausea and VomitingTimepoint: 15min,30min,45min,60min,75min,90min,105min,120min.—

Secondary

MeasureTime frame
Comparison Of Postoperative Pain Between Two GroupsTimepoint: 24 Hours;INTRAOPERATIVE HEMODYNAMIC STABILITY BETWEEN TWO GROUPSTimepoint: 2 HOURS—

Countries

India

Contacts

Public ContactArko Misra

Rajarajeswari Medical College and Hospital

rashmi.rp16@gmail.com9986665365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026