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Comparison of two different doses of Dexmedetomidine (a drug used for extending the duration of action of Spinal anaesthesia) with the routinely used drug (Bupivacaine) in Spinal Anaesthesia in patients undergoing surgeries below the umbilicus (navel region).

Comparison of two different doses of Dexmedetomidine as an additive to spinal anaesthesia in patients undergoing infra-umbilical surgeries: A Prospective Randomized Clinical Trial in Tertiary Care Centre. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058817
Enrollment
120
Registered
2023-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Group D1 - 15mgs(3ml) of 0.5% hyperbaric bupivacaine along with 3µgs of Inj. Dexmedetomidine: All the patients in Group D1 receive 15mgs(3ml) of 0.5% hyperbaric bupivacaine along with 3

Sponsors

Dr Gayathri Subhash Banasode
Lead Sponsor
Dr Nisheed Joseph
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 120 adult patients between the age group of 20-65yrs of physical status American Society of Anesthesiologists Physical Status I and II who undergo infra umbilical surgeries e.g.: Inguinal hernia repair surgeries, varicose vein surgeries, lower limb surgeries, etc.

Exclusion criteria

Exclusion criteria: Uncooperative patients, patients with uncontrolled hypertension, and diabetes, patients with allergy to the study drugs, patients on antiarrhythmics, beta-blockers, anticoagulants, ACE inhibitors, pregnant women, body weight >120kg, Heart Rate < 60 beats per minute and patients having a condition which is a contraindication to spinal anaesthesia such as patient refusal, infection at the site of injection, coagulopathy, increased intracranial pressure.

Design outcomes

Primary

MeasureTime frame
To evaluate the pain after two different doses of dexmedetomidine 3µg and 5µg, as an additive to hyperbaric bupivacaine 0.5% via intrathecal route (Spinal).Timepoint: Baseline, 1st hour,2nd hour,4th hour and 6th hour.

Secondary

MeasureTime frame
Onset and duration of sensory and motor block, hemodynamic effects, duration of analgesia, and occurrence of side effects.Timepoint: 6 hours

Countries

India

Contacts

Public ContactDr Gayathri Subhash Banasode

Kodagu Institute of Medical Sciences

gayathrinisheed@gmail.com9130512613

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026