Chronic Calcific Pancreatitis Study

Comparison of analgesic effectiveness of ultrasound-guided Erector Spinae Plane Intra Thecal Opioid (ESPITO) analgesia with Thoracic Epidural Analgesia (TEA) in patients undergoing open upper abdominal surgery for chronic calcific pancreatitis (CCP): A two-center assessor blinded randomized controlled non-inferiority trial - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058807

Enrollment

Registered

2023-10-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Thoracic Epidural Analgesia: The procedure will be performed under aseptic precautions in the operation theatre complex at the participating hospitals. After establishing an intravenous

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients diagnosed with chronic calcific pancreatitis with intractable pain scheduled for elective open pancreatic surgery who are willing to consent

Exclusion criteria

Exclusion criteria: Participants unwilling to provide consent Patients undergoing emergency pancreatic surgery Participants with known history of drug allergy to bupivacaine Participants who have received a coeliac plexus block

Design outcomes

Primary

Measure	Time frame
Mean Numerical Rating Scale (NRS) pain scores on coughingTimepoint: Mean Numerical Rating Scale (NRS) pain scores on coughing	—

Secondary

Measure	Time frame
Numerical Rating Scale on coughingTimepoint: 1, 6, 16, 40, 48, 64 and 72 hours after surgery;Mean Numerical Rating Scale (NRS) pain scores at restTimepoint: 1, 6, 16, 24, 40, 48, 64 and 72 hours after surgery;Patient satisfaction with pain managementTimepoint: 72 hours after surgery;Tramadol consumptionTimepoint: 72 hours after surgery;Complication with pain management techniqueTimepoint: 72 hours after surgery;Complication with surgeryTimepoint: 30 days after surgery;Total post operative Intravenous fluids usedTimepoint: 72 hours after surgery	—

Measure

Time frame

Numerical Rating Scale on coughingTimepoint: 1, 6, 16, 40, 48, 64 and 72 hours after surgery;Mean Numerical Rating Scale (NRS) pain scores at restTimepoint: 1, 6, 16, 24, 40, 48, 64 and 72 hours after surgery;Patient satisfaction with pain managementTimepoint: 72 hours after surgery;Tramadol consumptionTimepoint: 72 hours after surgery;Complication with pain management techniqueTimepoint: 72 hours after surgery;Complication with surgeryTimepoint: 30 days after surgery;Total post operative Intravenous fluids usedTimepoint: 72 hours after surgery

—

Countries

India

Contacts

Public ContactDr Niraj Gopinath

Sri Madhusudan Sai Institute of Medical Sciences and Research

niraj.gopinath@smsimsr.org9036119279

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026