Health Condition 1: R652- Severe sepsis
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Research institution
Eligibility
Inclusion criteria
Inclusion criteria: 1.Critically ill patients admitted in ICU with features of Sepsis 2.Microbiological culture confirmed CRE infection (Pulmonary and Blood stream) 3.Patients who have received CAZ/AVI or Polymyxins for at least 72 hours
Exclusion criteria
Exclusion criteria: 1.Polymicrobial cultures 2.Patients who have already received CAZ/AVI or Polymyxins before ICU admission 3.Patients with CKD 4.Patients with chemotherapy or immunosuppressant therapy in last three months • Post organ transplant patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine and compare Clinical success rate between two groups of patients Timepoint: 14 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To determine & compare length of ICU stay between two groups of patients 2. To determine and compare bacteriological clearance within 72 hours of antibiotic initiation 3. Evaluation of side effects between two groups Timepoint: 72 hours 14 days | — |
Countries
India
Contacts
Public ContactNeha Bhardwaj
Army Hospital, Research and Referral
Outcome results
None listed