Health Condition 1: K318- Other specified diseases of stomach and duodenum
Conditions
Interventions
Intervention1: ARGON PLASMA COAGULATION(APC): In this study, standard APC equipment will be used in 30 patients,
consisting of a highfrequency electrosurgical generator (ICC 350
ERBE, Germany), an automatically regulated argon source (APC
300) and a flexible APC probe. The APC probe is a 2.3 mm Tefloncoated catheter with a thermo-resistant ceramic top, which could be
passed t
Sponsors
MMCSBY Scheme Govt of Rajasthan
Eligibility
Inclusion criteria
Inclusion criteria: Patients’ = 18 years of age who present with obvious or occult blood loss, after confirming GAVE as the source, by upper GI endoscopy morphological features. All types of morphology of GAVE, irrespective of pattern will be included.
Exclusion criteria
Exclusion criteria: 1.Patients with bleeding peptic ulcers, bleeding esophageal or gastric varices or any other active source of bleeding identified with the aid of EGD, other than GAVE. 2. Patients previously received endotherapy (APC or EBL) for GAVE eradication 3.Patients on anti-platelet or anticoagulant therapy. 4.Patients with Hemorrhagic blood diseases. 5.Patients with Lymphoproliferative disorders. 6.Patients with advanced malignancy. 7.Patients with hemorrhagic PHG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is to identify obliteration of endoscopic visible GAVE lesions & number of treatment sessions needed for complete obliteration. Timepoint: Primary outcome is to identify obliteration of endoscopic visible GAVE lesions & number of treatment sessions needed for complete obliteration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are pre- & post-treatment haemoglobin values, absolute change in haemoglobin value, number of blood transfusions needed. All other quantitative & qualitative parameters in two separate groups will be considered secondaryTimepoint: Sessions will be performed every 3-4 weeks until complete eradication of GAVE lesions is achieved. Thereafter, all patients will be kept on a monthly follow up of their clinical & laboratory parameters for 6 months. | — |
Countries
India
Contacts
Public ContactDr Shashank Singh
SMS Medical College Jaipur
Outcome results
None listed