Health Condition 1: I110- Hypertensive heart disease with heart failure
Conditions
Interventions
Intervention1: Injection Nitroglycerine ( High dose ): In the intervention group, the patients will receive high dose nitroglycerin starting at a rate of 100 mcg/min via infusion pump, after manual me
Sponsors
Dr Satyabrata Guru
Eligibility
Inclusion criteria
Inclusion criteria: All patients above 18 years of age from either gender with SBP > 160mmHg and/or MAP >120mmHg with any one of the following i. Tachypnea (respiratory rate >30cpm). ii. Dyspnea (Borg dyspnea scale, use of accessory muscles, air hunger). iii. Hypoxia (SpO2 iv. Crepitations on auscultation. v. B lines over anterior lung fields on USG.
Exclusion criteria
Exclusion criteria: i. Patient refusal or inability to give informed consent. ii. Pregnancy. iii. Clinical suspicion of non-cardiogenic pulmonary edema. iv. Patients in whom proper recording of vitals during NTG infusion is not done. v. Patients requiring mechanical ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of high dose & low dose nitroglycerin infusion in the resolution of symptoms in the management of hypertensive acute pulmonary edema. Timepoint: 1 day | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the time taken by high dose & low dose nitroglycerin in the reduction of systolic BP by 25% of its initial value. 2. To compare the number of patients developing hypotension.Timepoint: 2 day | — |
Countries
India
Contacts
Public ContactDr Diya Ann Varghese
AIIMS,Bhubaneswar
Outcome results
None listed