Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Fentanyl: 2mcg/Kg of fentany diluted to 5 ml with normal saline , given intravenously immediately followed by injection lidocaine1.5mg/kg intravenouslydiluted to normal saline iv
Cont
Sponsors
non
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient with the history of difficult intubation 2. Patient with anticipated difficult airway 3. Patients having history of endocrine, cardiovascular, renal or CNS disease. 4. Patient having BMI > 30 kg m-2 5. Patient on anti-hypertensive or narcotic drugs
Exclusion criteria
Exclusion criteria: 1. Patient with the history of difficult intubation 2. Patient with anticipated difficult airway 3. Patients having history of endocrine, cardiovascular, renal or CNS disease. 4. Patient having BMI > 30 kg m-2 5. Patient on anti-hypertensive or narcotic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the heart rate & systolic blood pressure of two groups following laryngoscopy & intubation.Timepoint: i. Preoperative (baseline values) i.e. before injection of study drug ii. Before induction of anaesthesia (after injection of study drug) iii. After induction of anaesthesia i.e. just before laryngoscopy & intubation iv. Post intubation at 0min, 1 min, 2 min, 3min, 5min, 7min, 10min and 15min v. Then every 15 min till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the diastolic & mean blood pressure following laryngoscopy & intubation between two groups 2. To compare post-operative pain by VAS score 3. To compare post-operative sedation score ?Timepoint: Post intubation at 0min, 1 min, 2 min, 3min, 5min, 7min, 10min & 15min v. Then every 15 min till the end of surgery 1. Haemodynamic parameters (HR, SBP, DBP, MAP, SpO2) will be recorded at 0 min, then every 15 minutes for 1 hour and then every hour for next 2 hours post operatively. 2. Following post-operative parameters will be recorded at 0, 1, 2, & 3 hrs i) Pain (VAS) score ii) Sedation score | — |
Countries
India
Contacts
Public ContactMahendra Kumar
School of medical science and research, Sharda university
Outcome results
None listed