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A study on the association between mast cell number in skin, itch and quality of life in patients with Psoriasis

A study on the association between mast cell population, severity of pruritus and quality of life in patients with Psoriasis. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058689
Enrollment
28
Registered
2023-10-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L400- Psoriasis vulgaris

Interventions

Intervention1: NIL: NIL Intervention2: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Regina Jacob Brahmakulam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients consenting for the study who have been diagnosed with Psoriasis Vulgaris either based on typical clinical features and/or histopathological criteria. Patients should be off topical and oral treatment for psoriasis for the past 2 months either due to drug default, new flare in previously controlled disease, or in a treatment-naive patient.Patients will not be asked to withhold the treatment for study purposes.

Exclusion criteria

Exclusion criteria: Patients who have a history of atopy, bronchial asthma, allergic rhinitis, chronic sponatneous urticaria, angioedema, monoclonal mast cell activation syndrome and mastocytosis.

Design outcomes

Primary

MeasureTime frame
mast cell number (density) between lesional and peri-lesional skin of the same patientsTimepoint: at baseline—

Secondary

MeasureTime frame
5-D itch score, PASI and DQLITimepoint: at the same time of sample taking—

Countries

India

Contacts

Public ContactRegina Jacob Brahmakulam

Amala institute of medical sciences

drnazeerkv@gmail.com9847211237

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026