Health Condition 1: O-
Conditions
Interventions
None listed
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age more than 18 years 2.Patients willing for participation in the study. 3.All patients presenting in emergency with secondary peritonitis on clinical examination and radiological investigations.
Exclusion criteria
Exclusion criteria: 1.Patients operated outside GMCH and later referred to the centre. 2.Patients with other causes of raised procalcitonin levels which include chronic renal disease, neuro-endocrine tumours, heat stroke, Kawasaki disease, graft vs host disease, following granulocyte transfusions, treatment with interleukin-2 and carcinoid syndrome. 3.Patients with other causes of peritonitis which includes spontaneous bacterial peritonitis and tertiary peritonitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum procalcitonin as a predictor of clinical outcomesTimepoint: Levels of serum procalcitonin will be assessed once at the time of admission and then between 48 to 72 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mannheim peritonitis index, CRP and lactate levels in correlation to serum procalcitonin levels as predictors of clinical outcome in patients with secondary peritonitisTimepoint: 1 month;Serum procalcitonin levels as a predictor of surgical site infections, postoperative ICU requirement and mechanical ventilatory support, prolonged hospital stay lasting more than 7 days and mortality.Timepoint: 1 month;Total serum protein and albumin levels along with seum procalcitonin as predictors of anastomotic leak in patients with secondary peritonitisTimepoint: 1 month | — |
Countries
India
Contacts
Public ContactLakshya Nagpal
Government Medical College and Hospital
Outcome results
None listed