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This study is to determine whether cfDNA and DNA integrity Index have any role in managaement of colon cancer In response to surgery, cfDNA and DNA integrity index may play a key role in determining the outcome of colon cancer patients

Role of cfDNA and DNA Integrity Index in colon cancer in response to surgery - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058468
Enrollment
40
Registered
2023-10-10
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K638- Other specified diseases of intestine

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Regional Cancer Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pathologically diagnosed patients with colon cancer primary resection Stage T1-4, N1-2, M0 consent to participate in the study

Exclusion criteria

Exclusion criteria: WBC >10000 coexisting 2nd malignancy (other than colon cancer) acute and chronic infectious conditions(including septicemia) mental illness who could not cooperate with normal medical activities. chronic diseases: renal (CRF), hepatic(CLD), and heart (CAD) autoimmune diseases

Design outcomes

Primary

MeasureTime frame
To assess the level of cfDNA at baseline and after curative resection in patients with colon cancerTimepoint: before surgery and 4 weeks after surgery—

Secondary

MeasureTime frame
1) The clinical & tumor related factors deciding baseline cf DNA levels 2) The clinical & tumor related factors affecting the DNA integrity index 3) To compare cfDNA with CEA level in response to surgery & correlate their levels Timepoint: before surgery & 4 weeks after surgery—

Countries

India

Contacts

Public Contactdr Vipul Goyal

Regional Cancer Centre

drchandramohan@gmail.com04712522572

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026