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A comparison between Percutaneous Vertebroplasty procedure and Teriparatide injection in management of vertebral compression fracture, resulting from bone mineral loss.

A comparative study between fluoroscopy guided percutaneous vertebroplasty and teriparatide injection in treatment of acute and subacute osteoporotic vertebral compression fracture. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058456
Enrollment
38
Registered
2023-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fluoroscopy guided percutaneous vertebroplasty.: Vertebroplasty is done for osteoporotic compression vertebral fracture, under C-arm guidance, in transpedicular approach. Intervention2:

Sponsors

Institue of Postgraduate Medical Education and Research SSKM Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient diagnosed as Osteoporosis as per WHO criteria [T score of 2. Vertebral compression fracture on spine radiograph (minimum height loss 15%). 3. Low back pain for last 6 months or less. 4. Visual analogue scale (VAS) score > 3. 5. Bone edema of vertebral fracture on MRI.

Exclusion criteria

Exclusion criteria: 1. Spinal instability 2. Radicular pain or Radiculopathy 3. Abnormal coagulation profile 4. Systemic or local infection 5. Severe cardio-pulmonary comorbidities, uncontrolled liver and kidney diseases 6. Uncontrolled Diabetes mellitus 7. Underlying malignant disease 8. Loss of vertebral height =80% or vertebra plana, pedicle fracture, burst fracture and Scoliosis 9. Greater than 3 compression fractures 10. Patient’s refusal 11. Allergy to local anesthetic or PMMA, or Teriparatide.

Design outcomes

Primary

MeasureTime frame
Reduction in pain measured by Visual Analogue ScaleTimepoint: 6 month—

Secondary

MeasureTime frame
Quality of Life measured by using QUALEFFO 41 questionnaire.Timepoint: 6 month—

Countries

India

Contacts

Public ContactRajesh Pramanik

Institue of Postgraduate Medical Education and Research, SSKM Hospital

rpramanik2000@yahoo.com9432594882

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026