None listed
Conditions
Interventions
Intervention1: Alverise Cream: Approx. 50 mg, Neat, Single application on volar forearms
Intervention2: Alvextra Cream: Approx. 50 mg, Neat, Single application on volar forearms
Intervention3: Sotil
Sponsors
Encore Healthcare Pvt. Ltd.
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy adult males and/or non-pregnant/non-lactating females with age 18 to 65 years (both inclusive at the time of consent). 2. Subjects having good general health as determined by the Investigator on the basis of medical history. 3. Female subjects of childbearing potential must have a negative urine pregnancy test performed at enrollment visit. 4. Subjects willing to follow all the acceptable forms of contraception as applicable. 5. Subjects with dry / normal skin. • Subjects with self-perceived normal skin. • Subjects with dry (readings between 30 – 40) as assessed by MoisturemeterSC.
Exclusion criteria
Exclusion criteria: 1. Subjects using Body milk /lotion / cream, cosmetics or any other body moisturizing product 3-5 days prior to study. 2. Subjects who are on systemic medication or any medications would compromise the study. 3. Chronic illness which may influence the cutaneous state. 4. Subjects having history of diabetes. 5. Subjects with known allergy or sensitivity to cosmetic products and/or any ingredients of the test product.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effectiveness of test product in improving skin hydration/moisturization using MoistureMeterSCTimepoint: Day 01 [(Before application (i.e., baseline) and after application at 01 hour (plus 15 mins), 04 hours (plus 15 mins) and 6 hours (plus 15 mins)] and on Day 02 [24 hours (plus 15 mins) after application]. | — |
Secondary
| Measure | Time frame |
|---|---|
| Product Perception QuestionnaireTimepoint: Day 02 [24 hours plus 15 mins) after application].;To evaluate the effectiveness of test product in improving the skin barrier function by measuring Transepidermal Water Loss (TEWL) using VapometerTimepoint: Day 01 [(Before application (i.e., baseline) and after application at 01 hour (plus 15 mins), 04 hours (plus 15 mins) and 6 hours (plus 15 mins)] and on Day 02 [24 hours (plus 15 mins) after application].;To evaluate the effectiveness of test product in improving the skin physical parameter by Dermatologist | Dermatologist Validated Scorer using 5-point scoring scale for skin dryness, skin roughness, skin redness/erythema, burning, itching and stinging and 8-point scoring scale for skin suppleness and softnessTimepoint: Day 01 [(Before application (i.e., baseline) and after application at 01 hour (plus 15 mins), 04 hours (plus 15 mins) and 6 hours (plus 15 mins)] and on Day 02 [24 hours (plus 15 mins) after application]. | — |
Countries
India
Contacts
Public ContactDr Simran Sethi
Cliantha Research
Outcome results
None listed