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Evaluation of effectiveness of macrolides in patients of chronic rhinosinusitis

Evaluation of efficacy of macrolides in eradication of biofilms in patients of chronic rhinosinusitis - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058444
Enrollment
18
Registered
2023-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: nil: nil

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with chronic rhinosinusitis

Exclusion criteria

Exclusion criteria: 1. Patients who took intranasal corticosteroid spray and antibiotics within the last one month 2. Known cases of bronchial asthma 1. Known immunocompromised patients 2. Pregnant females 3. Patients with mucociliary dysfunction (e.g. Cystic Fibrosis, Kartagener’s syndrome) 4. Patients with a history of prior nasal surgery 5. Patients with known cardiac illness or those with long QT syndrome

Design outcomes

Primary

MeasureTime frame
The percentage change in biofilm positivity in patients of Chronic rhinosinusitis after administration of intranasal corticosteroid spray & macrolide antibiotic (Clarithromycin) for 2 weeks.Timepoint: 2 weeks.—

Secondary

MeasureTime frame
1. The proportion of patients with biofilm in Chronic rhinosinusitis. 2. The spectrum of bacteria forming biofilm in Chronic rhinosinusitis.Timepoint: 2 weeks—

Countries

India

Contacts

Public ContactDr Akash M Lal

Maulana Azad Medical College

taneja_hc@yahoo.com9868399555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026