A study to assess the effects of two drugs,topical methotrexate gel and topical mometasone furoate ointment in patients with psoriasis.

Comparative study of topical methotrexate gel 1% and topical mometasone furoate ointment 0.1% in the treatment of stable plaque psoriasis. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058439

Enrollment

Registered

2023-10-09

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L400- Psoriasis vulgaris

Interventions

Intervention1: Topical Methotrexate gel 1%: Group B will receive topical Methotrexate gel 1% twice daily for 8 weeks Control Intervention1: Topical Mometasone furoate ointment (0.1%): Group A will rec

Eligibility

Inclusion criteria

Inclusion criteria: 1.Not using topical psoriasis treatment for at least 2weeks before the start of study. 2.Patients having mild to moderate chronic plaque psoriasis.

Exclusion criteria

Exclusion criteria: 1.Use of Phototherapy,PUVA or systemic therapy for psoriasis within 8 weeks before the start of study. 2.Pregnant and lactating women and women of child bearing potential who are not practicing an acceptable method of birth control. 4.Patients of unstable,erythrodermic,pustular and guttate psoriasis.

Design outcomes

Primary

Measure	Time frame
1.Efficacy of topical methotrexate gel 1% and topical mometasone furoate ointment 0.1% in the treatment of psoriasisTimepoint: Lesions will be scored at baseline and after 2,4,6 and 8 weeks of treatment	—

Secondary

Measure	Time frame
to determine the safety profile,tolerability of topical MTX gel and Mometasone furoate ointmentTimepoint: At 2,4,6 and 8 weeks of treatment.	—

Countries

India

Contacts

Public ContactDr Shivani

Indira Gandhi Institute of Medical Sciences

sinhaderma@gmail.com7764049225

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026