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Drug mediated pupil constriction and its association with dose requirement of pain killers during surgery

Fentanyl mediated pupillary constriction and its association with intraoperative fentanyl requirement in patients undergoing laparoscopic surgeries: an observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058437
Enrollment
88
Registered
2023-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K353- Acute appendicitis with localizedperitonitis Health Condition 2: K806- Calculus of gallbladder and bile duct with cholecystitis Health Condition 3: K819- Cholecystitis, unspecified

Interventions

Intervention1: NIL: NIL

Sponsors

Bharathi Hosdurg
Lead Sponsor
Shathish Kumar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients underoing laparoscopic surgeries . 2.Patient under American society of Anaesthesiologists (ASA) I - III.

Exclusion criteria

Exclusion criteria: 1. Patients with any eye injuries 2. Patients with any head injuries 3. Patients whose pupil diameter could not be measured due to technical failure 4. Patients whose surgical duration is less than 30 minutes 5. Patients with any substance abuse 6. Patients treated with opioids preoperatively for any acute or chronic pain

Design outcomes

Primary

MeasureTime frame
Intraoperative fentanyl requirementTimepoint: 0 hour to end of surgery—

Secondary

MeasureTime frame
Postoperative pain score measured on numerical rating scaleTimepoint: 1-hour postoperative period;Sedation score measured on Ramsay sedation scaleTimepoint: 1-hour postoperative period;Postoperative nausea and vomiting scores (Visual analogue scale and PONV intensity scale)Timepoint: 1-hour postoperative period;Intraoperative depth of anaesthesia (minimum alveolar concentration)Timepoint: Not applicatble;Time taken to recover from anaesthesiaTimepoint: Not applicable—

Countries

India

Contacts

Public ContactShathish Kumar

Manipal Hospital Whitefield

bharathisunil61@gmail.com9900190920

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026