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To understand usage pattern, and effectiveness of sacubitril/valsartan in heart failure

Retrospective, electronic medical records (EMR) based study to understand usage pattern and effectiveness of sacubitril/valsartan in heart failure - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058403
Enrollment
1000
Registered
2023-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I462- Cardiac arrest due to underlying cardiac condition

Interventions

Intervention1: Nil: Nil

Sponsors

Dr Reddys Laboratories Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Heart failure Patients who have been prescribed with CIDMUS and ejection fraction (EF) value are reported at baseline. 2.Patients of either sex =18 years of age

Exclusion criteria

Exclusion criteria: Patients for whom EF value is not reported at baseline

Design outcomes

Primary

MeasureTime frame
1. To evaluate the usage of sacubitril/valsartan across different ranges of EF (=40%, 41-49%, =50%) – signifying HF with reduced EF (HFrEF), HF with moderately reduced EF (HFmrEF), & HF with preserved EF (HFpEF), respectively. 2.To understand baseline demographics – patients’ age, gender, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), comorbid conditions and concomitant medications like beta blocker [BB], mineralocorticoid receptor antagonist [MRA], Sodium-glucose cotransporter-2 [SGLT2] inhibitors and combinations) as monotherapy and/or combination therapy in HF patients on sacubitril/valsartan.Timepoint: 2017 to 2023 (Data will be captured for one consecutive follow-up visit from the baseline visit/index date)

Secondary

MeasureTime frame
• The effect of CIDMUS on change in EF from baseline • Change in SBP, & DBP from baseline to follow up visits • Change in potassium levels from baseline to follow up visit • Average dose & dose titrations of CIDMUS Timepoint: 2017 to 2023 (Data will be captured for one consecutive follow-up visit from the baseline visit/index date)

Countries

India

Contacts

Public ContactDr Rahul Rathod

Dr Reddys Laboratories Limited

simranchhatwal@drreddys.com9582711359

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026