A study to identify the optimal preemptive analgesic dose of gabapentin

Evaluation of two different doses of Gabapentin given as preemptive analgesia for Lumbar Laminectomy- A Randomized Double-Blind Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058395

Enrollment

Registered

2023-10-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Preemptive analgesia per oral: Two different doses of gabapentin for postoperative analgesia given preoperatively Intervention2: Gabapentin: 300mg, oral, two hours preoperatively Contro

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA 1 and 2 patients undergoing elective lumbar laminectomy under general anesthesia

Exclusion criteria

Exclusion criteria: 1) ASA 3 and 4 2) Pregnant and lactating patients 3) Patients on maintenance dose of gabapentin for any indication 4) Emergency surgery 5) Drug allergy to gabapentin or any common drugs that are used during general anesthesia 6) Prolonged surgery more than 4 hours

Design outcomes

Primary

Measure	Time frame
1) Postoperative pain measured using Visual Analogue Scale 2) Consumption of rescue analgesicTimepoint: 0,1,2,4,6,8,12,24 hours postoperatively	—

Secondary

Measure	Time frame
1) Modified Ramsay Sedation Score 2) Postoperative nausea and vomitingTimepoint: 0,1,2,4,6,8,12,24 hours postoperatively	—

Countries

India

Contacts

Public ContactAswathi M P

Lourdes hospital

write2koshy@gmail.com9446573477

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026