Administration of ketamine into spinal Anaesthesia to prevent post amputation perception of pain in a limb that is no longer there.

Effect of intrathecal Ketamine in prevention of Phantom limb pain following lower extremity amputation surgeries: A randomized clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058385

Enrollment

Registered

2023-10-06

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: subarachnoid block: Under strict aseptic precautions, using 27G Whitacre spinal needle, subarachnoid block is administered using study drug preparation between L3 and L4 intervertebral

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient undergoing elective lower extremity amputation under Subarachnoid Block 2. Age between 18-65 years old 3. American Society of Anaesthesiologists (ASA) I & II

Exclusion criteria

Exclusion criteria: 1.Patients known allergic to either of the study drugs [Bupivacaine or Ketamine]. 2.Patients with neuro-behavioural changes, severe diabetic /autonomic neuropathy. 3.Patients on long term analgesic medications and contraindicated for subarachnoid block. 4. Patients who failed follow ups for pain evaluation. 5. Patients who undergo further amputation during the follow up period are excluded from the further analysis.

Design outcomes

Primary

Measure	Time frame
Post operatively patient is developing the perception of pain or discomfort in a limb that is no longer there.Timepoint: from 6 hours to 6 months postoperatively	—

Secondary

Measure	Time frame
To assess the incidence and severity of post amputation phantom limb pain.Timepoint: from 6 hours to 6 months postoperatively	—

Countries

India

Contacts

Public ContactKathija Begam A

Jawaharlal Nehru Medical College ,Belagavi

drvinayakjannu84@gmail.com9743908033

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026