Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis Health Condition 3: O- Medical and Surgical Health Condition 4: K808- Other cholelithiasis
Conditions
Interventions
Intervention1: Intravenous Ibuprofen in Laparoscopic Cholecystectomy: 400 mg Ibuprofen infusion compared with 100 ml Normal Saline infusion 15 minutes pre-operatively
Control Intervention1: Ibuprofen
Sponsors
Rabindranath Tagore Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients of ASA grade I-II 2) Patients scheduled for laparoscopic cholecystectomy surgeries
Exclusion criteria
Exclusion criteria: 1) Patients not fulfilling eligibility criteria 2) Lack of patient consent 3) Drug dependence 4) History of long-term NSAIDs and opioid analgesic use 5) Patients allergic to ibuprofen 6) Patients with diabetes or other neuropathic diseases 7) History of gastrointestinal bleeding, peptic ulcer or inflammatory bowel disease, asthma 8) Patients with severe hepatic or renal failure 9) Patients weighing less than 40 Kg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| post operative analgesiaTimepoint: 24 hours post-operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) hemodynamic changes 2) the time to first analgesic requirement and VAS score post operatively 3) Adverse effectsTimepoint: 24 hours post-operatively | — |
Countries
India
Contacts
Public ContactDr Pallavi Gangwani
Rabindranath Tagore Medical College, Udaipur
Outcome results
None listed