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The effect of blood-derived products on bone healing after surgery : A randomized clinical trial

The effect of concentrated growth factor (SGF) and Platelet Rich Fibrin (PRF) on post endodontic surgery healing : A randomized clinical trial - Nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058270
Enrollment
30
Registered
2023-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: M268- Other dentofacial anomalies Health Condition 3: K046- Periapical abscess with sinus

Interventions

Intervention1: Concentrated Growth factor, Platelet rich fibrin: Concentrated Growth factor, Platelet rich fibrin total duration of intervention- 6 months Control Intervention1: Periapical surgery wi

Sponsors

Supriya Choudhary
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients within 18–40 years of age. Single rooted, anterior teeth. Teeth with peri apical radiolucency indicated for surgery. Patients who are not on any medication affecting periapical healing. (corticosteroids, chemotherapeutic agents, non ?steroidal anti ? inflammatory drugs (NSAIDs), antibiotics, anticoagulants and drugs which reduce osteoclastic activity).

Exclusion criteria

Exclusion criteria: Patients who did not give their consent for participating in the study. Patients having insufficient motivation to report back for follow up visits. Patients with any systemic diseases like diabetes mellitus, hypertension, hepatitis, Human immunodeficiency virus, bone disorders, auto ?immune disorders. Surgical retreatment cases. Patients with malignant tumors or undergoing chemotherapy/ radiotherapy. Pregnant females. Patients with periodontally compromised teeth.

Design outcomes

Primary

MeasureTime frame
Surface area reductionTimepoint: 0,1,3,6 months

Secondary

MeasureTime frame
Peak systolic velocityTimepoint: 0,1,3,6 months

Countries

India

Contacts

Public ContactSupriya choudhary

FODS, KGMU

rameshbharti@kgmcindia.edu993572473

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026