Health Condition 1: O80- Encounter for full-term uncomplicated delivery
Conditions
Interventions
Intervention1: Sequential use of Mifepristone, Dinoprostone And Misoprostol For induction of labor: Day(cycle) 1- Single dose of Mifepristone 200MG P/O
• Day(cycle) 2- Single dose of Dinoprostone gel
Sponsors
Dr Asmita Yadav
Eligibility
Inclusion criteria
Inclusion criteria: Singleton, live gestation • Primi and Multigravida • Gestational age between 37 weeks 0 days - 42 weeks 0 days • Fetus in cephalic presentation • Patients admitted for labor induction • Patients who are not in labor with intact membranes • Patients with no contraindication for vaginal delivery
Exclusion criteria
Exclusion criteria: Significant cardiac, renal, or hepatic maternal comorbidities, severe gestational hypertension or preeclampsia with severe features ? Pregnancies complicated by major fetal anomalies ? Pregnancies complicated by fetal growth restriction (Estimated fetal weight <10%) ? Fetuses with an estimated fetal weight >4500 gm by recent ultrasound or Leopold's exam on admission ? Any indication for scheduled cesarean delivery ? Hypersensitivity to prostaglandins
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vaginal & Caesarean delivery rates with each sequential cycleTimepoint: Day 1 Day 2 Day 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate maternal (Intrapartum chorionamnionitis, Post partum hemorrhage rates, ICU admissions) and perinatal outcomes (Birth weight, APGAR scores, Meconium stained amniotic fluid, NICU admissions) with sequential cycles of above mentioned agentsTimepoint: Day 1 Day 2 Day 3 | — |
Countries
India
Contacts
Public ContactDr. Rajani Upadhyaya
Kasturba Medical College, Manipal
Outcome results
None listed