To compare which drug combination is better ketamine- dexmedetomidine versus ketamine-propofol combination in patients undergoing laparoscopic appendectomy under anesthesia

The Effect of intravenous ketamine- dexmedetomidine versus ketamine-propofol in patients undergoing laparoscopic appendicectomy under spinal anaesthesia – A randomized clinical trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058228

Enrollment

Registered

2023-10-04

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: intravenous dexmedetomidine: the effectiveness of intravenous ketamine-dexmedetomidine infusion will be compared with intravenous ketamine-propofol infusion in patients undergoing lapa

Eligibility

Inclusion criteria

Inclusion criteria: • ASA I and ASA II patients. • Age between 18 to 60yrs. • Weight 35-70 kg. • Gender -both sex. • Elective laparoscopic appendectomy

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. ASA III and ASA IV 3. Patients with cardiac disease and chronic obstructive airway disease. Patients with a history of allergic reaction to Propofol, ketamine, or dexmedetomidine • Bleeding diathesis • Obese patients.

Design outcomes

Primary

Measure	Time frame
Intraoperative Hemodynamic stabilityTimepoint: 60 to 120 minutes	—

Secondary

Measure	Time frame
Sedation score, Time to regain consciousness and complicationsTimepoint: 60 to 120 minutes	—

Countries

India

Contacts

Public ContactDRSHANMUGAVALLIE

Aarupadai veedu medical college and hospital

vallijegan@gmail.com

Outcome results