Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Control Intervention1: Administration of Fentanyl IV(2mcg/kg) or Dexmedetomidine IV(0.5mcg/kg), followed by Propofol IV administration: Group D received intravenous dexmedetomidine at 0.5mcg/kg recons
Sponsors
Dr Fayaz Musthafa
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age group 18 to 55 years, undergoing elective surgeries under general anaesthesia. - Patients classified under American Society of Anaesthesiologists (ASA) 1 and 2 after thorough Pre-Anaesthetic evaluation.
Exclusion criteria
Exclusion criteria: 1.Patient refusal 2.Pregnant women 3.Patients with BMI of 30kg/m2 and more 4.Patients with history of epilepsy, and patients who are currently on anti-epileptic medication 5.Patients with anticipated difficult airway – Mallampatti Grade 3 or 4, short neck. 6.Patients with history of allergy to Propofol, Fentanyl or Dexmedetomidine 7.Patients undergoing emergency surgeries. 8.Patients with history of alcohol abuse, drug abuse.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To assess hemodynamic stability. - to assess adverse effects, if any.Timepoint: To assess hemodynamic stability from the time of induction to the time of laryngoscopy and intubation. | — |
Primary
| Measure | Time frame |
|---|---|
| The outcome is to determine the dose at which propofol causes loss of verbal contact, when administered after usage of fentanyl or dexmedetomidine.Timepoint: Monitoring is done at 1-minute interval, for 8 minutes, from the time of administration of fentanyl or dexmedetomidine, to the time of intubation. | — |
Countries
India
Contacts
Public ContactDr Mahesh Chandra
Rajarajeswari Medical College and Hospital
Outcome results
None listed