Spinal anaesthesia comparison between plain hyperbaric drug and drug with adjuvant combination in inguinal hernia open surgery

A comparative study between plain hyperbaric ropivacaine versus hyperbaric ropivacaine versus hyperbaric ropivacaine with nalbuphine under spinal anaesthesia in patients undergoing open inguinal hernia mesh repair - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/058224

Enrollment

Registered

2023-10-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Hyperbaric ropivacaine and nalbuphine: Intrathecal administartion of hyperbaric ropivacaine 3ml + Inj. Nalbuphine 0.8mg reconstituted to 0.5 ml with sterile normal saline. Duration of a

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I and II male patients. 2. Patients undergoing elective unilateral open inguinal hernia repair.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Allergy to opioids and local anesthetics. 3. Morbidly obese patients. 4. Patients with coagulation abnormalities. 5. Previous spine surgeries and spinal deformities. 6. Mentally retarded patients. 7. Infection at the site of injection. 8. Patients having neurological abnormalities.

Design outcomes

Primary

Measure	Time frame
To compare the effect of adding 0.8mg of Nalbuphine to 0.75% hyperbaric Ropivacaine vs plain 0.75% hyperbaric Ropivacaine for unilateral inguinal hernia open mesh repair surgeries under spinal anaesthesia.Timepoint: Duration of analgesia in the first 24 hours post surgery	—

Secondary

Measure	Time frame
To assess: Time of onset of sensory and motor blockade. Time of regression of segments of sensory blockade. Time of regression of motor blockade. Hemodynamic response. Adverse effects if any. Total analgesic consumption in 24 hours. Timepoint: Intraoperative onset of motor and sensory blockade. Intraoperative and postoperative regression of motor and sensory blockade.	—

Countries

India

Contacts

Public ContactKarthik G S

Rajarajeswari Medical College and Hospital

drgskarthik@gmail.com9538220515

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026