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Development of A Generic Blood Test Based on Gene Signatures To Diagnose Hepatocellular Carcinoma Patients

Development of A Generic Blood Diagnostic Methodology Based on Gene Signatures To Investigate Mutational Status Of Hepatocellular Carcinoma Patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/10/058191
Enrollment
400
Registered
2023-10-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C220- Liver cell carcinoma

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Mohamed Rela
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients with a diagnosis of hepatocellular carcinoma on imaging 2. All patients with a suspicion of hepatocellular caricnoma based on imaging or tumour markers (elevated AFP, PIVKA) 3. Patients undergoing surgery (resection or transplant) for hepatocellular carcinoma 4. Patients undergoing palliative care modalities (chemotherapy, immunotherapy, embolisation etc) for hepatocellular carcinoma

Exclusion criteria

Exclusion criteria: 1. Age below 18 years, or above 80 years 2. patients with liver tumors other than hepatocellular carcinoma 3. Patients who refuse to enroll for the study

Design outcomes

Primary

MeasureTime frame
To determine the mutational status of HCC patients to prognosticate the tumourTimepoint: 15 days, 1,3,6 months, 1 year, 18 months, 2 years

Secondary

MeasureTime frame
To correlate and predict risk of recurrence with existing biomarkers - alpha fetoprotein and PIVKATimepoint: 15 days, 1,3,6 months, 1 year, 18 months, 2 years

Countries

India

Contacts

Public ContactDr Vasanthakumar Gunasekaran

Dr. Rela Institute and Medical Centre

vasanth_smc@yahoo.co.in08861401250

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026