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Comparison of two medicines to reduce shivering after spinal anaesthesia

Comparative evaluation of oral Tramadol vs Gabapentin for prophylaxis of post spinal shivering -A Randomised control study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/058182
Enrollment
150
Registered
2023-10-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Control Intervention1: Tramadol: Tramadol, a µ opioid receptor agonist also inhibits neuronal uptake of noradrenaline and promotes hydroxytryptamine secretion. Single dose of T

Sponsors

Nancy Prasanna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 &2 Age 20-59 BMI-18-30 Both Sex Posted for elective surgeries under spinal Anaesthesia

Exclusion criteria

Exclusion criteria: Administration of blood and blood products Infusion of cold crystalloid Solution Patients with cardiopulmonary disease, Psychological disorders, uncooperative patients. History of allergy to opioids or gabapentin, patients already taking Tramadol or Gabapentinoids History of opioid abuse Febrile Patients Patients with diabetic autonomic neuropathy Prolonged surgical time leading to supplementation/conversion to general anaesthesia

Design outcomes

Primary

MeasureTime frame
To compare the incidence and severity of postspinal shivering with prophylactic oral gabapentin, tramadol and placeboTimepoint: Recorded immediately when the patient made supine and thereafter at every 5 min for 1 h and every 10 min till the effect of block weaned off.

Secondary

MeasureTime frame
To compare the occurance of any side effects like nausea & vomiting / sedationTimepoint: Till the effect of block weaned off

Countries

India

Contacts

Public ContactNANCY PRASANNA

St.johns medical College

Shilpa.j.rao@gmail.com9986784722

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026