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Study including trial of pre-emptive analgesia in patient with MIH in which patients having high sensitivity due to low mineralization

Comparing the effectiveness of preemptive post operative & combination of preemptive & post operative ibuprofen therapy in children with molar incisor hypomineralization - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/058044
Enrollment
150
Registered
2023-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: ibuprofen: group- 1 400mg ibuprofen given orally 1 hour prior to procedure and 400mg ibuprofen orally 6 hours after initial dose group -2 400mg ibuprofen 1 hour before procedure group-3

Sponsors

Mira virda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Children with dental hypersensitivity and at least 1st permanent molar affected with hypomineralization 2.Children who are not allergic to analgesics or local anesthesia. 3.The children ranges between 7-10 years. 4.Co-operative children, either positive or definitely positive according to frankel behaviour rating scale.

Exclusion criteria

Exclusion criteria: 1.Non co-operative children 2.The children with amelogenesis imperfecta and dentinogenesis imperfecta 3.The children with history of prolonged bleeding, hypersensitivity or allergic reaction to analgesics 4.The children whose parents have not given concern.

Design outcomes

Primary

MeasureTime frame
To evaluate the effectiveness of preemptive analgesia in pain perception in children with molar incisor hypomineralization & hypersensitivity Timepoint: pain assesment after local anesthesis, after procedure and 2 hours post operatively

Secondary

MeasureTime frame
immediate post operative pain may be reduced & the development of chronic pain may be reduced Molar incisor hypomineralization is often accompanied by dental hypersensitivity & difficulty in achieving effective analgesia so to check the effect of preemptive drugs on hypersensitivity in MIH. Timepoint: After giving local anesthesia, post opertively & 2 hours after procedure

Countries

India

Contacts

Public ContactMira virda

College of Dental science and research center

mirakataria14@gmail.com6351113441

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026