A Randomised Study for effect of treatment on Quantitative Electroencephalogram in persons with Alcohol Dependence Syndrome

Changes in Quantitative Electroencephalogram in Persons with Alcohol Dependence Syndrome with Treatment – A Randomised Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057998

Enrollment

Registered

2023-09-25

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H- Substance Abuse Treatment

Interventions

Intervention1: Lorazepam: Benzodiazepine used for Detoxification. Dose: Based on symptom triggered regimen. Initiation dose of 4 mg/day and uptitration of 1 mg/day Frequency: Daily, as per withdrawal

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with Alcohol Dependence Syndrome as per ICD-11 criteria. 2. Alcohol withdrawal assessment scoring guidelines (CIWA-AR) score moderate withdrawals as per Maudsley guidelines) 3. Age groups 25 and above. 4. Male gender.

Exclusion criteria

Exclusion criteria: 1. Patients who are known cases of epilepsy. 2. Patient dependent on other substances except nicotine and caffeine 3. Patients with past history of complicated withdrawals 4. Patients who are intoxicated or are in severe withdrawals. 5. Patients with comorbid active psychotic illness. 6. Actively suicidal patients. 7. Patients with any acute medical or surgical illness.

Design outcomes

Primary

Measure	Time frame
Use of Quantitative Electroencephalogram as screening and diagnostic tool for alcohol use disorder.Timepoint: 1. At baseline 2. After completion of detoxification (CIWA-Ar 3. After 3 months	—

Secondary

Measure	Time frame
Comparison and assessment of anxiety and depression from baseline by using scales - HAM-A, HAM-D.Timepoint: 1. At baseline 2. After completion of detoxification (CIWA-Ar 3. After 3 months;Comparison of Lorazepam and Diazepam with reference to changes in Quantitative Electroencephalogram along with objective scale scores on SADQ and CIWA-Ar.Timepoint: 1. At baseline 2. After completion of detoxification (CIWA-Ar 3. After 3 months	—

Measure

Time frame

Comparison and assessment of anxiety and depression from baseline by using scales - HAM-A, HAM-D.Timepoint: 1. At baseline 2. After completion of detoxification (CIWA-Ar 3. After 3 months;Comparison of Lorazepam and Diazepam with reference to changes in Quantitative Electroencephalogram along with objective scale scores on SADQ and CIWA-Ar.Timepoint: 1. At baseline 2. After completion of detoxification (CIWA-Ar 3. After 3 months

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Countries

India

Contacts

Public ContactDr Ajeet Sidana

Government Medical College and Hospital, Sector 32, Chandigarh

ajeetsidana@hotmail.com9056422679

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026