Better pretreatment agent to reduce pain associated with propofol injection pain between ketamine vs lidocaine injection at the time of induction of general anaesthesia during surgical procedures

A randomised comparative study of ketamine vs lidocaine to decrease propofol injection pain during induction of anaesthesia in patients undergoing surgery under general anaesthesia at department of anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057987

Enrollment

170

Registered

2023-09-25

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K566- Other and unspecified intestinal obstruction

Interventions

Intervention1: A RANDOMISED COMPARATIVE STUDY OF KETAMINE VS LIDOCAINE TO DECREASE PROPOFOL INJECTION PAIN DURING INDUCTION OF ANESTHESIA IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIA: Comp

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients willing to participate in the study 2.Patients with age between 18 years to 55 years. 3.American Society of Anaesthesiologist (ASA) Grade I and II. 4.Undergoing elective urological, Gynaecological or general surgical procedures. 5.Patients undergoing routine elective surgical procedures under General anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patients not willing to participate in study 2.Patients with history of known hypersensitivity to Propofol injectable emulsion or any of its components. 3.Pregnant women. 4.Nursing mothers. 5.Morbid obesity (BMI >35). 6.Chronic steroid use. 7.Patients on antidepressants or opioid dependence or suffering from any psychiatric disease 8.Patients with chronic pain (arthritis, malignancies). 9.Those having difficulty in venous access 10.Uncontrolled hypertension

Design outcomes

Primary

Measure	Time frame
Incidence & severity of pain of propofol injection with a verbal response & behavioural signs such as facial grimacing,arm withdrawal or tears at different time intervals 0 seconds 1 minutes 2 minutesTimepoint: 2 minutes	—

Secondary

Measure	Time frame
Hemodynamic variables 1 HR 2 SBP 3 DBP 4 SpO2Timepoint: 20 minutes	—

Countries

India

Contacts

Public ContactManoj kumar soni

Sms medical college jaipur

manoj_sithal@yahoo.com9829472797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026