Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Hyoscine: Intravenous administration of 1 ml of Hyoscine Butylbromide which contains 20 mg diluted to 2 ml, one minute after spinal anaesthesia.
Control Intervention1: Ondansetron: Intr
Sponsors
Dr Anwesha Bayan
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age group: 18 to 35 years 2. ASA physical status 2. 3. Normal singleton pregnancy with a gestational period of minimum 32 weeks. 4. Elective caesarean section under spinal anaesthesia. 5. Informed and written consent will be taken.
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA: 1. Allergy to study drugs. 2. Patient with known coagulopathy or patients on anticoagulation therapy. 3. Patient’s height 180 cm. 4. Patient with pregnancy induced hypertension 5. Patient with gestational diabetes mellitus 6. Patient with fetal distress 7. Patient with cardiac disease 8. Patient with Kidney disease 9. Patient with morbid obesity 10. BMI >35 kg per metre square 11. baseline bradycardia (HR- 60 bpm) or tachycardia (HR more than or equal to 100 bpm)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of intraoperative bradycardia between the two groups.Timepoint: To compare the incidence of intraoperative bradycardia between the two groups at 0, 1, 3, 6, 9, 15, 20, 30, 40, 50 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare fetal APGAR score between the two groups.Timepoint: At 1 minute & 5 minutes.;To compare the changes in intraoperative hemodynamics between the two groups.Timepoint: Intraoperatively.;To compare the incidence of intraoperative nausea & vomiting between the two groups.Timepoint: Intraoperatively.;To compare the incidence of post operative nausea & vomiting between the two groups.Timepoint: 2 hours. | — |
Countries
India
Contacts
Public ContactDr Anwesha Bayan
Gauhati Medical College and Hospital
Outcome results
None listed