Surgery alone versus Surgery with Extensive intraperitoneal lavage for locally advanced gastric cancer -A comparison of short term postoperative outcomes

Surgical site infection in patients undergoing D2 Gastrectomy alone versus D2 Gastrectomy with Extensive intraperitoneal lavage for locally advanced gastric cancer -A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057983

Enrollment

108

Registered

2023-09-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C169- Malignant neoplasm of stomach, unspecified

Interventions

Intervention1: Extensive Intraperitoneal Lavage along with surgery in patients with locally advanced gastric adenocarcinoma: This proposal for the study uses standard of care procedure of intraperiton

Eligibility

Inclusion criteria

Inclusion criteria: All the patients who are more than 18 years of age and preoperatively - cT3 or 4 N0-3 M0 (according to AJCC, 8th edition) undergoing open total or subto-tal gastrectomy for locally advanced gastric adenocarcinoma, with ECOG performance status 0 or 1

Exclusion criteria

Exclusion criteria: 1. Received neoadjuvant therapy. 2. Patients with co-existing uncontrolled comorbidities. 3. Recurrent carcinoma of stomach. 4. Presence of other coexisting malignancy. 5. Other types of gastric cancer such as lym-phoma, GIST, carcinoid tumor. 6. Emergency gastrectomy for bleeding or per-forated gastric cancer.

Design outcomes

Primary

Measure	Time frame
To compare the effect of extensive intraperitoneal lavage with surgery & surgery alone on the incidence of surgical site infection in patients undergoing D2 gastrectomy for locally advanced carcinoma of stomach.Timepoint: Upto 30 days from the day of surgery.	—

Secondary

Measure	Time frame
1. Postoperative pain (using Visual Analogue Scale) 2. Gastrointestinal (GI) complications such as: a. Bowel obstruction/ileus. b. Anastomotic leak. 3. Non-GI complications such as: a. Pulmonary complications (atelectasis, pleural effusion, Pulmonary thromboembolism). b. Deep vein thrombosis (DVT). c. Pneumonia. 4. Reoperation. 5. Readmission rates within 30 days 6. Mortality within 30 days of surgery Timepoint: Upto 30 days from the day of surgery.	—

Measure

Time frame

1. Postoperative pain (using Visual Analogue Scale) 2. Gastrointestinal (GI) complications such as: a. Bowel obstruction/ileus. b. Anastomotic leak. 3. Non-GI complications such as: a. Pulmonary complications (atelectasis, pleural effusion, Pulmonary thromboembolism). b. Deep vein thrombosis (DVT). c. Pneumonia. 4. Reoperation. 5. Readmission rates within 30 days 6. Mortality within 30 days of surgery Timepoint: Upto 30 days from the day of surgery.

—

Countries

India

Contacts

Public ContactDr Sreenath G S

Jawaharlal Institute of Postgraduate Medical Education and Research

Dr.sreenathgs@gmail.com9486690883

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026