Comparison between two local anaesthetics for use in Spinal Anaesthesia in Patients undergoing Gynaecological Surgeries

Comparison Of Analgesic Efficacy Of Hyperbaric Ropivacaine (0.75%) with Hyperbaric Bupivacaine (0.5%) for Spinal Anaesthesia in Gynaecological Surgeries: A Double-Blind Randomised Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057971

Enrollment

110

Registered

2023-09-22

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N809- Endometriosis, unspecified Health Condition 2: N819- Female genital prolapse, unspecified Health Condition 3: N829- Female genital tract fistula, unspecified Health Condition 4: N979- Female infertility, unspecified Health Condition 5: N926- Irregular menstruation, unspecified Health Condition 6: N849- Polyp of female genital tract, unspecified Health Condition 7: N96- Recurrent pregnancy loss Health Condition 8: N949- Unspecified condition associated with female genita

Interventions

Intervention1: Spinal Anaesthesia with Hyperbaric Ropivacaine(0.75%): To determine duration of analgesia produced by the drug and note any adverse events during intraoperative and postoperative period

Eligibility

Inclusion criteria

Inclusion criteria: 1. patients undergoing elective gynaecological surgeries under spinal anaesthesia 2.patients who have given written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Patient with any contraindication to spinal anaesthesia 2. Patient having uncontrolled systemic disease 3. Patient undergoing emergency Surgery 4. Patient with known allergy to the drugs used

Design outcomes

Primary

Measure	Time frame
duration of sensory block produced after intrathecal administration Timepoint: Intraoperative and postoperative period	—

Secondary

Measure	Time frame
compare the haemodynamic changes (heart rate, blood pressure) between the two groupsTimepoint: Intraoperative and postoperative period;compare the onset of motor (muscle paralysis) and sensory blocks with Ropivacaine vs Bupivacaine Timepoint: Intraoperative period;compare the time of first requirement of rescue analgesia (pain relief) in the patients of the two groupsTimepoint: Postoperative period	—

Measure

Time frame

compare the haemodynamic changes (heart rate, blood pressure) between the two groupsTimepoint: Intraoperative and postoperative period;compare the onset of motor (muscle paralysis) and sensory blocks with Ropivacaine vs Bupivacaine Timepoint: Intraoperative period;compare the time of first requirement of rescue analgesia (pain relief) in the patients of the two groupsTimepoint: Postoperative period

—

Countries

India

Contacts

Public ContactProf Subrata Kumar Mandal

College of Medicine and Sagore Dutta Hospital

drsubrata2010@gmail.com9433175801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026