Comparative Evaluation of two commercially available toothpastes on Glucosyltransferase Enzyme

Comparative Evaluation of two commercially available toothpastes on the reduction of Glucosyltransferase Enzyme - a Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057967

Enrollment

Registered

2023-09-22

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Commercially available toothpaste containing Salvadora persica (miswak) extract: A commercially available toothpaste containing miswak extract under the brand name, Dabur Meswak, will b

Eligibility

Inclusion criteria

Inclusion criteria: Participants with atleast 1 active carious lesion.

Exclusion criteria

Exclusion criteria: Medically compromised individuals. Patients with a history of allergic reactions. Patients undergoing orthodontic treatment.

Design outcomes

Primary

Measure	Time frame
Glucosyltransferase enzyme absorption index by ELISATimepoint: Baseline, 6 months	—

Secondary

Measure	Time frame
Assessment of DMFS status using ICDAS-II scoringTimepoint: Baseline, 3 months, 6 months, 9 months, 12 months;Assessment of microbial count in terms of colony forming unitsTimepoint: Baseline, 3 months, 6 months, 9 months, 12 months	—

Countries

India

Contacts

Public ContactIpsitha Vejendla

Saveetha Dental college and Hospital

krithikadatta.sdc@saveetha.com9840111369

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026