Health Condition 1: H104- Chronic conjunctivitis
Conditions
Interventions
Intervention1: Tacrolimus 0.03% eye ointment: Twice daily for 3weeks followed by once daily for 3 weeks.
Control Intervention1: Tacrolimus 0.01% eye ointment: Twice daily for 3 weeks followed by once
Sponsors
KAHER JGMM Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >14yrs 2.Active bilateral severe VKC responding poorly despite >1 month of treatment with topical anti allergic agents and corticosteroids.
Exclusion criteria
Exclusion criteria: 1.Patients with adnexal abnormalities, glaucoma, contact lens wearer, corneal pathology will be excluded from the study. 2.Patients who have received immunosuppressive therapy 3.Patients with known hypersensitivity to Tacrolimus eye ointment 4.Pregnant and lactating women will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in mean scores of ocular symptoms and signs at 2nd week, 4th week, 6th week and 8th week from baseline. Timepoint: All the parameters will be evaluated at baseline visit, day 14, day 30 & day 45. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures: 1.Subjective scoring of symptoms at baseline, 2nd week, 4th week, 6th week & 8th week. 2.Any adverse effects from the treatment reported. Timepoint: All the parameters will be evaluated at baseline visit, day 14, day 30 & day 45. | — |
Countries
India
Contacts
Public ContactMeghana Patil
KLE Academy of Higher Education, Jagadguru Gangadhar Mahaswamigalu Moorsavirmath Medical College
Outcome results
None listed