Comparing budesonide nasal spray and water based gel as an lubricant on endotracheal tube cuff to know the incidence of sore throat after general anaesthesia.

Comparison of budesonide spray and water based as an endotracheal tube cuff lubricant on incidence of post operative sore throat:Randomized control study. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057923

Enrollment

178

Registered

2023-09-21

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: K-Y gel: Before intubation, k-y gel 82gm is applied on endothracheal tube cuff Tropical route and it will be a one time of application before the starting of surgery Control Interventio

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria : 1) American socity of Anaesthesiolgist classification grade 1 and 2. 2)Eective surgery under general anaesthesia with endotracheal intubation not lasting for more than 3 hours. A thorough pre anaesthetic evaluation will be done oery, nil per mouth status will be confirmed, and intravenous cannula will be secured. For all the patients, aspiration prophylaxis of IV Inj. Pantoprazole 40mg, and IV Inj. Ondansetron 8mg will be given. After shifting the patient to operation theatre, in all patients, pre medication of IV Inj. Glycopyrolate .005mg/kg, IV Inj. Midazolam .05mg/kg and IV Inj. Fentanyl 2mcg/kg. General anaesthesia will be induced with IV Inj. Propofol 2mg/kg with IV Inj. Succinylcholine 2mg/kg. Endotracheal cuff will be lubricated with Budesonide 200mcg spray in one group, and water based KY gel 82gm in another group. Intubation will be done. Anaesthesia will be maintained with titrated dose of Isoflurane, oxygen, and nitrous oxide. IV bolus of Inj. Vecuronium .1mg/kg or Inj. Atracurium .5mg/kg will be repeated intermittentanly to maintain muscle relaxation. After adequate reversal at the end of surgery, thourough oropharyngeal suctioning, and regaining of consciousness, patient will be extubated, following which patient will be shifted to Post Anaesthtic Care Unit where post operative sore throat will be graded in the time intervals of immediately, 10 mins, 1st hour, 6th hour, and 24th hour after extubation.

Exclusion criteria

Exclusion criteria: 1)pre operative sore throat. 2)patients already pn a analgesic or steriods. 3)peptic ulcer and gastroesophageal reflux disease 4)Chronic lung disease. 5)Allergic to study drug

Design outcomes

Primary

Measure	Time frame
To know the incidence of Post operative sore throat after extubationTimepoint: Immediately, 10minutes, 1st Hour, 6th Hour and 24th Hours after extubation	—

Countries

India

Contacts

Public ContactSUMA CHAVADI

JAWAHARLAL NEHRU MEDICAL COLLEGE BELAGAVI

drchaitanya12@gmail.com8150038305

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026