Health Condition 1: L811- Chloasma
Conditions
Interventions
Intervention1: 30% Metformin lotion at night for 2 months: patients are asked to apply 30% metformin lotion at night over melasma for 2 months
Control Intervention1: topical zinc oxide cream bd for 2
Sponsors
NITHYAMS
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of both genders above 18 years who were clinically diagnosed to have melasma 2.Patients willing to give a written informed consent
Exclusion criteria
Exclusion criteria: Before starting the study 1. Pregnant & lactating mothers 2. Patients on oral contraceptives, phenytoin 3. Patients with unrealistic expectations 4. Patients who are allergic to metformin 5. Patients on medications for melasma since at least 2 weeks for topical therapy, 1 month for systemic steroids, 3 months for cosmetic procedures such as laser, dermabrasion, or peels 6. Patients with co-morbidities-DM, SHTN, TB,CAD,EPILEPSY,BA, carcinomas, Renal dysfunction, During Study 1. If patient develops side effects during the treatment 2. If patient wants alternate treatment during the study. 3. If patient wants to discontinue the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in intensity of pigmentationTimepoint: 8 weeks after using medication | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevention of relapseTimepoint: 1 year | — |
Countries
India
Contacts
Public ContactDrNithyaMS
chengalpattu govt.medical college
Outcome results
None listed